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Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning
A plaque assay—the gold-standard method for measuring the concentration of replication-competent lytic virions—requires staining and usually more than 48 h of runtime. Here we show that lens-free holographic imaging and deep learning can be combined to expedite and automate the assay. The compact im...
Autores principales: | Liu, Tairan, Li, Yuzhu, Koydemir, Hatice Ceylan, Zhang, Yijie, Yang, Ethan, Eryilmaz, Merve, Wang, Hongda, Li, Jingxi, Bai, Bijie, Ma, Guangdong, Ozcan, Aydogan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427422/ https://www.ncbi.nlm.nih.gov/pubmed/37349390 http://dx.doi.org/10.1038/s41551-023-01057-7 |
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