Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation

Our current understanding of biomolecular condensate formation is largely based on observing the final near-equilibrium condensate state. Despite expectations from classical nucleation theory, pre-critical protein clusters were recently shown to form under subsaturation conditions in vitro; if simil...

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Detalles Bibliográficos
Autores principales: Lan, Chenyang, Kim, Juhyeong, Ulferts, Svenja, Aprile-Garcia, Fernando, Weyrauch, Sophie, Anandamurugan, Abhinaya, Grosse, Robert, Sawarkar, Ritwick, Reinhardt, Aleks, Hugel, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427612/
https://www.ncbi.nlm.nih.gov/pubmed/37582808
http://dx.doi.org/10.1038/s41467-023-40540-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427612/
https://www.ncbi.nlm.nih.gov/pubmed/37582808
http://dx.doi.org/10.1038/s41467-023-40540-2

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