COMPASS: joint copy number and mutation phylogeny reconstruction from amplicon single-cell sequencing data

Reconstructing the history of somatic DNA alterations can help understand the evolution of a tumor and predict its resistance to treatment. Single-cell DNA sequencing (scDNAseq) can be used to investigate clonal heterogeneity and to inform phylogeny reconstruction. However, most existing phylogeneti...

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Detalles Bibliográficos
Autores principales: Sollier, Etienne, Kuipers, Jack, Takahashi, Koichi, Beerenwinkel, Niko, Jahn, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427627/
https://www.ncbi.nlm.nih.gov/pubmed/37582954
http://dx.doi.org/10.1038/s41467-023-40378-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427627/
https://www.ncbi.nlm.nih.gov/pubmed/37582954
http://dx.doi.org/10.1038/s41467-023-40378-8

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