Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models

Duchenne muscular dystrophy is caused by mutations in the DMD gene, leading to lack of dystrophin. Chronic muscle damage eventually leads to histological alterations in skeletal muscles. The identification of genes and cell types driving tissue remodeling is a key step to developing effective therap...

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Detalles Bibliográficos
Autores principales: Heezen, L.G.M., Abdelaal, T., van Putten, M., Aartsma-Rus, A., Mahfouz, A., Spitali, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427630/
https://www.ncbi.nlm.nih.gov/pubmed/37582915
http://dx.doi.org/10.1038/s41467-023-40555-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427630/
https://www.ncbi.nlm.nih.gov/pubmed/37582915
http://dx.doi.org/10.1038/s41467-023-40555-9

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