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Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models
Duchenne muscular dystrophy is caused by mutations in the DMD gene, leading to lack of dystrophin. Chronic muscle damage eventually leads to histological alterations in skeletal muscles. The identification of genes and cell types driving tissue remodeling is a key step to developing effective therap...
Autores principales: | Heezen, L.G.M., Abdelaal, T., van Putten, M., Aartsma-Rus, A., Mahfouz, A., Spitali, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427630/ https://www.ncbi.nlm.nih.gov/pubmed/37582915 http://dx.doi.org/10.1038/s41467-023-40555-9 |
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