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NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis

Cell fate and proliferation ability can be transformed through reprogramming technology. Reprogramming glioblastoma cells into neuron-like cells holds great promise for glioblastoma treatment, as it induces their terminal differentiation. NeuroD4 (Neuronal Differentiation 4) is a crucial transcripti...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Zhao, Peiqi, Zhang, Ying, Chen, Zhen, Bao, Han, Qian, Wenqi, Wu, Jian, Xing, Zhenqiu, Hu, Xiaowei, Jin, Kunlin, Zhuge, Qichuan, Yang, Jianjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427652/
https://www.ncbi.nlm.nih.gov/pubmed/37582760
http://dx.doi.org/10.1038/s41420-023-01595-8