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Pervasive genotype-by-environment interactions shape the fitness effects of antibiotic resistance mutations

The fitness effects of antibiotic resistance mutations are a major driver of resistance evolution. While the nutrient environment affects bacterial fitness, experimental studies of resistance typically measure fitness of mutants in a single environment only. We explored how the nutrient environment...

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Detalles Bibliográficos
Autores principales: Soley, Jake K., Jago, Matthew, Walsh, Calum J., Khomarbaghi, Zahra, Howden, Benjamin P., Lagator, Mato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427823/
https://www.ncbi.nlm.nih.gov/pubmed/37583318
http://dx.doi.org/10.1098/rspb.2023.1030