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Joint models quantify associations between immune cell kinetics and allo-immunological events after allogeneic stem cell transplantation and subsequent donor lymphocyte infusion

Alloreactive donor-derived T-cells play a pivotal role in alloimmune responses after allogeneic hematopoietic stem cell transplantation (alloSCT); both in the relapse-preventing Graft-versus-Leukemia (GvL) effect and the potentially lethal complication Graft-versus-Host-Disease (GvHD). The balance b...

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Detalles Bibliográficos
Autores principales: Koster, Eva A. S., Bonneville, Edouard F., Borne, Peter A. von dem, van Balen, Peter, Marijt, Erik W. A., Tjon, Jennifer M. L., Snijders, Tjeerd J. F., van Lammeren, Daniëlle, Veelken, Hendrik, Putter, Hein, Falkenburg, J. H. Frederik, Halkes, Constantijn J. M., de Wreede, Liesbeth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427852/
https://www.ncbi.nlm.nih.gov/pubmed/37593737
http://dx.doi.org/10.3389/fimmu.2023.1208814