Oxaliplatin-induced peripheral neurotoxicity in colorectal cancer patients: mechanisms, pharmacokinetics and strategies

Oxaliplatin-based chemotherapy is a standard treatment approach for colorectal cancer (CRC). However, oxaliplatin-induced peripheral neurotoxicity (OIPN) is a severe dose-limiting clinical problem that might lead to treatment interruption. This neuropathy may be reversible after treatment discontinu...

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Detalles Bibliográficos
Autores principales: Cheng, Fang, Zhang, Ruoqi, Sun, Chen, Ran, Qian, Zhang, Cuihan, Shen, Changhong, Yao, Ziqing, Wang, Miao, Song, Lin, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427877/
https://www.ncbi.nlm.nih.gov/pubmed/37593174
http://dx.doi.org/10.3389/fphar.2023.1231401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427877/
https://www.ncbi.nlm.nih.gov/pubmed/37593174
http://dx.doi.org/10.3389/fphar.2023.1231401

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