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Oxaliplatin-induced peripheral neurotoxicity in colorectal cancer patients: mechanisms, pharmacokinetics and strategies
Oxaliplatin-based chemotherapy is a standard treatment approach for colorectal cancer (CRC). However, oxaliplatin-induced peripheral neurotoxicity (OIPN) is a severe dose-limiting clinical problem that might lead to treatment interruption. This neuropathy may be reversible after treatment discontinu...
Autores principales: | Cheng, Fang, Zhang, Ruoqi, Sun, Chen, Ran, Qian, Zhang, Cuihan, Shen, Changhong, Yao, Ziqing, Wang, Miao, Song, Lin, Peng, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427877/ https://www.ncbi.nlm.nih.gov/pubmed/37593174 http://dx.doi.org/10.3389/fphar.2023.1231401 |
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