Impact of mAb-induced A475V substitution on viral fitness and antibody neutralization of SARS-CoV-2 omicron variants in the presence of monoclonal antibodies and human convalescent sera

The emergence and rapid evolution of SARS-CoV-2 variants have posed a major challenge to the global efforts to control the COVID -19 pandemic. In this study, we investigated the potential of two SARS-CoV-2 variants, BA.2 and BA.5, to evade neutralization by a human monoclonal antibody targeting the...

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Detalles Bibliográficos
Autores principales: Viriyakitkosol, Ratchanont, Wanitchang, Asawin, Srisutthisamphan, Kanjana, Saenboonreung, Janya, Boonkrai, Chatikorn, Pisitkun, Trairak, Jongkaewwattana, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427911/
https://www.ncbi.nlm.nih.gov/pubmed/37593745
http://dx.doi.org/10.3389/fimmu.2023.1219546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427911/
https://www.ncbi.nlm.nih.gov/pubmed/37593745
http://dx.doi.org/10.3389/fimmu.2023.1219546

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