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KLK2 single-nucleotide polymorphism rs198977 is associated with increased susceptibility and hyperleukocytosis in AML

Introduction: Acute myeloid leukemia (AML) is a heterogeneous myeloid malignancy with abnormal molecular diversity. Tissue kallikrein 2 (KLK2) is a kind of serine protease, and has a close relationship with the occurrence and development of malignant tumors. Single nucleotide polymorphism (SNP) of v...

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Detalles Bibliográficos
Autores principales: Meng, Guangqiang, Li, Peng, Li, Mingying, Wu, Yuyan, Ma, Yuechan, Sun, Tao, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427912/
https://www.ncbi.nlm.nih.gov/pubmed/37593117
http://dx.doi.org/10.3389/fgene.2023.1218523