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Hypomethylated interferon regulatory factor 8 recruits activating protein-2α to attenuate porcine epidemic diarrhea virus infection in porcine jejunum

Interferon regulatory factor 8 (IRF8) is a key regulator of innate immune receptor signaling that resists pathogen invasion by regulating cell growth and differentiation. Porcine epidemic diarrhea virus (PEDV) targets the intestine and damages the mucosal barrier. However, whether IRF8 regulates PED...

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Detalles Bibliográficos
Autores principales: Zong, Qiufang, Qu, Huan, Zheng, Xianrui, Wang, Haifei, Wu, Shenglong, Yin, Zongjun, Bao, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427914/
https://www.ncbi.nlm.nih.gov/pubmed/37593742
http://dx.doi.org/10.3389/fimmu.2023.1187144