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Genomic and Immune Features in an Intrahepatic Cholangiocarcinoma Patient with Microsatellite Instability-High Suffered Rapid Acquired Resistance to PD-1 Inhibitor

INTRODUCTION: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive liver malignancy with poor prognosis. Recently, the development of immune checkpoint inhibitors (ICIs), such as programmed cell death 1 (PD-1) inhibitors, has emerged as a promising strategy in multiple tumor types, including...

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Detalles Bibliográficos
Autores principales: Cheng, Zhuo, Zeng, Tianmei, Yang, Guang, Liu, Di, Zheng, Zhi, Yuan, Zhengang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427924/
https://www.ncbi.nlm.nih.gov/pubmed/37593364
http://dx.doi.org/10.1159/000530273