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Calcineurin B inhibits calcium oxalate crystallization, growth and aggregation via its high calcium-affinity property

Calcineurin inhibitors (CNIs) are widely used in organ transplantation to suppress immunity and prevent allograft rejection. However, some transplant patients receiving CNIs have hypocitraturia, hyperoxaluria and kidney stone with unclear mechanism. We hypothesized that CNIs suppress activities of u...

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Detalles Bibliográficos
Autores principales: Hadpech, Sudarat, Chaiyarit, Sakdithep, Thongboonkerd, Visith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10427926/
https://www.ncbi.nlm.nih.gov/pubmed/37593722
http://dx.doi.org/10.1016/j.csbj.2023.07.038