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Cellular and exosomal GPx1 are essential for controlling hydrogen peroxide balance and alleviating oxidative stress in hypoxic glioblastoma

Tumor hypoxia promotes malignant progression and therapeutic resistance in glioblastoma partly by increasing the production of hydrogen peroxide (H(2)O(2)), a type of reactive oxygen species critical for cell metabolic responses due to its additional role as a second messenger. However, the cataboli...

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Detalles Bibliográficos
Autores principales: Lei, Fu-Ju, Chiang, Jung-Ying, Chang, Huan-Jui, Chen, Der-Cherng, Wang, Hwai-Lee, Yang, Hsi-An, Wei, Kai-Yu, Huang, Yen‐Chih, Wang, Chi-Chung, Wei, Sung-Tai, Hsieh, Chia-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428075/
https://www.ncbi.nlm.nih.gov/pubmed/37572455
http://dx.doi.org/10.1016/j.redox.2023.102831