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Cellular and exosomal GPx1 are essential for controlling hydrogen peroxide balance and alleviating oxidative stress in hypoxic glioblastoma
Tumor hypoxia promotes malignant progression and therapeutic resistance in glioblastoma partly by increasing the production of hydrogen peroxide (H(2)O(2)), a type of reactive oxygen species critical for cell metabolic responses due to its additional role as a second messenger. However, the cataboli...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428075/ https://www.ncbi.nlm.nih.gov/pubmed/37572455 http://dx.doi.org/10.1016/j.redox.2023.102831 |