Circulating Tumor DNA Response and Minimal Residual Disease Assessment in DNA Polymerase Epsilon-Mutated Colorectal Cancer Undergoing Immunotherapy

Exonuclease domain mutation (EDM) in polymerase epsilon (POLE)-mutated colorectal cancer patients is characterized by specific clinical features and a very high tumor mutation burden (TMB). The therapeutic effectiveness of immune checkpoint inhibitors (ICIs) for the treatment of colorectal cancer in...

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Detalles Bibliográficos
Autores principales: Lutfi, Areeb, Afghan, Maaz K, Kasi, Pashtoon M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428188/
https://www.ncbi.nlm.nih.gov/pubmed/37593074
http://dx.doi.org/10.7759/cureus.43391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428188/
https://www.ncbi.nlm.nih.gov/pubmed/37593074
http://dx.doi.org/10.7759/cureus.43391

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