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Interaction of Radiopharmaceuticals with Somatostatin Receptor 2 Revealed by Molecular Dynamics Simulations

[Image: see text] The development of drugs targeting somatostatin receptor 2 (SSTR2), generally overexpressed in neuroendocrine tumors, is focus of intense research. A few molecules in conjugation with radionuclides are in clinical use for both diagnostic and therapeutic purposes. These radiopharmac...

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Detalles Bibliográficos
Autores principales: Gervasoni, Silvia, Öztürk, Işılay, Guccione, Camilla, Bosin, Andrea, Ruggerone, Paolo, Malloci, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428218/
https://www.ncbi.nlm.nih.gov/pubmed/37466559
http://dx.doi.org/10.1021/acs.jcim.3c00712