Cargando…

Complexity of Guanine Quadruplex Unfolding Pathways Revealed by Atomistic Pulling Simulations

[Image: see text] Guanine quadruplexes (GQs) are non-canonical nucleic acid structures involved in many biological processes. GQs formed in single-stranded regions often need to be unwound by cellular machinery, so their mechanochemical properties are important. Here, we performed steered molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Stadlbauer, Petr, Mlýnský, Vojtěch, Krepl, Miroslav, Šponer, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428220/
https://www.ncbi.nlm.nih.gov/pubmed/37458574
http://dx.doi.org/10.1021/acs.jcim.3c00171