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Integrated multi-omics analyses reveal Jorunnamycin A as a novel suppressor for muscle-invasive bladder cancer by targeting FASN and TOP1

BACKGROUND: Bladder cancer is a urological carcinoma with high incidence, among which muscle invasive bladder cancer (MIBC) is a malignant carcinoma with high mortality. There is an urgent need to develop new drugs with low toxicity and high efficiency for MIBC because existing medication has defect...

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Detalles Bibliográficos
Autores principales: Chen, Ruijiao, Hao, Xiaopeng, Chen, Jingyuan, Zhang, Changyue, Fan, Huixia, Lian, Fuming, Chen, Xiaochuan, Wang, Chao, Xia, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428641/
https://www.ncbi.nlm.nih.gov/pubmed/37587470
http://dx.doi.org/10.1186/s12967-023-04400-3