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Integrated multi-omics analyses reveal Jorunnamycin A as a novel suppressor for muscle-invasive bladder cancer by targeting FASN and TOP1
BACKGROUND: Bladder cancer is a urological carcinoma with high incidence, among which muscle invasive bladder cancer (MIBC) is a malignant carcinoma with high mortality. There is an urgent need to develop new drugs with low toxicity and high efficiency for MIBC because existing medication has defect...
Autores principales: | Chen, Ruijiao, Hao, Xiaopeng, Chen, Jingyuan, Zhang, Changyue, Fan, Huixia, Lian, Fuming, Chen, Xiaochuan, Wang, Chao, Xia, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428641/ https://www.ncbi.nlm.nih.gov/pubmed/37587470 http://dx.doi.org/10.1186/s12967-023-04400-3 |
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