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Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2–AKT–TGF-β Signaling Axis in Pancreatic Cancer

BACKGROUND & AIMS: Pancreatic cancer has the highest prevalence of cancer-associated cachexia among all cancers. ZIP4 promotes pancreatic cancer progression by regulating oncogenic miR-373, and perturbation of circular RNAs (circRNAs) is associated with cancer aggressiveness. This study aimed to...

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Detalles Bibliográficos
Autores principales: Shi, Xiuhui, Yang, Jingxuan, Liu, Mingyang, Zhang, Yuqing, Zhou, Zhijun, Luo, Wenyi, Fung, Kar-Ming, Xu, Chao, Bronze, Michael S., Houchen, Courtney W., Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10428768/
https://www.ncbi.nlm.nih.gov/pubmed/35176309
http://dx.doi.org/10.1053/j.gastro.2022.02.017