Comprehensive structural, infrared spectroscopic and kinetic investigations of the roles of the active-site arginine in bidirectional hydrogen activation by the [NiFe]-hydrogenase ‘Hyd-2’ from Escherichia coli

The active site of [NiFe]-hydrogenases contains a strictly-conserved pendant arginine, the guanidine head group of which is suspended immediately above the Ni and Fe atoms. Replacement of this arginine (R479) in hydrogenase-2 from E. coli results in an enzyme that is isolated with a very tightly-bou...

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Detalles Bibliográficos
Autores principales: Evans, Rhiannon M., Beaton, Stephen E., Rodriguez Macia, Patricia, Pang, Yunjie, Wong, Kin Long, Kertess, Leonie, Myers, William K., Bjornsson, Ragnar, Ash, Philip A., Vincent, Kylie A., Carr, Stephen B., Armstrong, Fraser A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430524/
https://www.ncbi.nlm.nih.gov/pubmed/37592998
http://dx.doi.org/10.1039/d2sc05641k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430524/
https://www.ncbi.nlm.nih.gov/pubmed/37592998
http://dx.doi.org/10.1039/d2sc05641k

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