Opportunities and challenges of protein-based targeted protein degradation

In the 20 years since the first report of a proteolysis targeting chimeric (PROTAC) molecule, targeted protein degradation (TPD) technologies have attempted to revolutionize the fields of chemical biology and biomedicine by providing exciting research opportunities and potential therapeutics. Howeve...

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Detalles Bibliográficos
Autores principales: Shen, Fangfang, Dassama, Laura M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430753/
https://www.ncbi.nlm.nih.gov/pubmed/37592990
http://dx.doi.org/10.1039/d3sc02361c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430753/
https://www.ncbi.nlm.nih.gov/pubmed/37592990
http://dx.doi.org/10.1039/d3sc02361c

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