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Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6(+) CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma

BACKGROUND: Various immune cell types in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) have been identified as important parameters associated with prognosis and responsiveness to immunotherapy. However, how various factors influence immune cell infiltration remains incompletely...

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Detalles Bibliográficos
Autores principales: Li, Xiaogang, Gao, Zheng, Chen, Jiafeng, Feng, Shanru, Luo, Xuanming, Shi, Yinghong, Tang, Zheng, Liu, Weiren, Zhang, Xin, Huang, Ao, Gao, Qiang, Ke, Aiwu, Zhou, Jian, Fan, Jia, Fu, Xiutao, Ding, Zhenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430781/
https://www.ncbi.nlm.nih.gov/pubmed/37593098
http://dx.doi.org/10.3389/fonc.2023.1099385