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Weight-adjusted dosing of fibrinogen concentrate and cryoprecipitate in the treatment of hypofibrinogenaemic bleeding adult cardiac surgical patients: a post hoc analysis of the Fibrinogen Replenishment in cardiac surgery randomised controlled trial

BACKGROUND: Hypofibrinogenaemia is associated with excessive bleeding after cardiac surgery. Our aim was to compare the efficacy and safety of weight-adjusted vs empiric dosing of fibrinogen replacement in cardiac surgery. METHODS: In the Fibrinogen Replenishment in Cardiac Surgery (FIBRES) RCT, pat...

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Detalles Bibliográficos
Autores principales: Devine, Cian, Bartoszko, Justyna, Callum, Jeannie, Karkouti, Keyvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430806/
https://www.ncbi.nlm.nih.gov/pubmed/37588266
http://dx.doi.org/10.1016/j.bjao.2022.100016