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Reduced excitatory neurotransmission in the hippocampus after inflammation and sevoflurane anaesthesia

BACKGROUND: Inflammation and general anaesthesia likely contribute to perioperative neurocognitive disorders, possibly by causing a neuronal imbalance of excitation and inhibition. We showed previously that treatment with lipopolysaccharide (LPS) and sevoflurane causes a sustained increase in a toni...

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Detalles Bibliográficos
Autores principales: Khodaei, Shahin, Wang, Dian-Shi, Orser, Beverley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10430808/
https://www.ncbi.nlm.nih.gov/pubmed/37588178
http://dx.doi.org/10.1016/j.bjao.2023.100143