Population pharmacokinetic analysis of sparsentan in healthy volunteers and patients with focal segmental glomerulosclerosis

Sparsentan is a single‐molecule dual endothelin angiotensin receptor antagonist (DEARA) currently under investigation as a treatment for focal segmental glomerulosclerosis (FSGS) and IgA nephropathy (IgAN). A population pharmacokinetic (PK) analysis was performed to characterize the PKs of sparsenta...

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Detalles Bibliográficos
Autores principales: Wada, Russell, Kleijn, Huub Jan, Zhang, Lu, Chen, Shang‐Chiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431048/
https://www.ncbi.nlm.nih.gov/pubmed/37221817
http://dx.doi.org/10.1002/psp4.12996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431048/
https://www.ncbi.nlm.nih.gov/pubmed/37221817
http://dx.doi.org/10.1002/psp4.12996

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