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Therapeutic Benefit of Melatonin in Choroidal Neovascularization During Aging Through the Regulation of Senescent Macrophage/Microglia Polarization

PURPOSE: This study aimed to investigate the age-dependent anti-angiogenic capability of melatonin in choroidal neovascularization (CNV) and to explore the underlying molecular mechanisms. METHODS: In the present study, a laser-induced CNV model was established in both young (three months of age) an...

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Detalles Bibliográficos
Autores principales: Cui, Kaixuan, Tang, Xiaoyu, Hu, Andina, Fan, Matthew, Wu, Peiqi, Lu, Xi, Lin, Jicheng, Yang, Fengmei, Zhao, Xinyu, Huang, Jingjing, Yu, Shanshan, Xu, Yue, Liang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431207/
https://www.ncbi.nlm.nih.gov/pubmed/37578424
http://dx.doi.org/10.1167/iovs.64.11.19