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The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

Infections by Human T cell Leukaemia Virus type 1 (HTLV-1) persist for the lifetime of the host by integrating into the genome of CD4(+) T cells. Proviral gene expression is essential for proviral survival and the maintenance of the proviral load, through the pro-proliferative changes it induces in...

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Detalles Bibliográficos
Autores principales: Aristodemou, Aris E. N., Rueda, David S., Taylor, Graham P., Bangham, Charles R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431621/
https://www.ncbi.nlm.nih.gov/pubmed/37523412
http://dx.doi.org/10.1371/journal.ppat.1011494