Hepatitis C virus non-structural proteins modulate cellular kinases for increased cytoplasmic abundance of host factor HuR and facilitate viral replication

Host protein HuR translocation from nucleus to cytoplasm following infection is crucial for the life cycle of several RNA viruses including hepatitis C virus (HCV), a major causative agent of hepatocellular carcinoma. HuR assists the assembly of replication-complex on the viral-3′UTR, and its deplet...

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Detalles Bibliográficos
Autores principales: Raheja, Harsha, George, Biju, Tripathi, Sachin Kumar, Saha, Sandhini, Maiti, Tushar Kanti, Das, Saumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431626/
https://www.ncbi.nlm.nih.gov/pubmed/37540723
http://dx.doi.org/10.1371/journal.ppat.1011552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431626/
https://www.ncbi.nlm.nih.gov/pubmed/37540723
http://dx.doi.org/10.1371/journal.ppat.1011552

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