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Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical Investigations

[Image: see text] In continuance of our investigation into the anticancer activity of oxadiazoles, we report here the preparation of 10 new 1,3,4-oxadiazole analogues using the scaffold hopping technique. We have prepared the oxadiazoles having a common pharmacophoric structure (oxadiazole linked ar...

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Detalles Bibliográficos
Autores principales: Agarwal, Mohit, Afzal, Obaid, Salahuddin, Altamimi, Abdulmalik Saleh Alfawaz, Alamri, Mubarak A., Alossaimi, Manal A., Sharma, Vandana, Ahsan, Mohamed Jawed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431697/
https://www.ncbi.nlm.nih.gov/pubmed/37593245
http://dx.doi.org/10.1021/acsomega.3c01462