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SIRT1 promotes the progression and chemoresistance of colorectal cancer through the p53/miR-101/KPNA3 axis

INTRODUCTION: Sirtuin 1 (SIRT1) is a key modulator in several types of cancer, including colorectal cancer (CRC). Here, we probed into the molecular mechanism of SIRT1 regulating the development and chemoresistance of CRC. METHODS: Differentially expressed genes related to the growth, metastasis and...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Wei, Jiang, Ying-Hao, Ye, Wei, Shao, Chun-Fa, Xie, Jian-Jin, Li, Xia
Formato: Online Artigo Texto
Idioma:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431729/
https://www.ncbi.nlm.nih.gov/pubmed/37575080
http://dx.doi.org/10.1080/15384047.2023.2235770