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Sclerostin small-molecule inhibitors promote osteogenesis by activating canonical Wnt and BMP pathways

BACKGROUND: The clinical healing environment after a posterior spinal arthrodesis surgery is one of the most clinically challenging bone-healing environments across all orthopedic interventions due to the absence of a contained space and the need to form de novo bone. Our group has previously report...

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Detalles Bibliográficos
Autores principales: Sangadala, Sreedhara, Kim, Chi Heon, Fernandes, Lorenzo M, Makkar, Pooja, Beck, George R, Boden, Scott D, Drissi, Hicham, Presciutti, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431921/
https://www.ncbi.nlm.nih.gov/pubmed/37560905
http://dx.doi.org/10.7554/eLife.63402