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Sex and cell-specific gene expression in corticolimbic brain regions associated with psychiatric disorders revealed by bulk and single-nuclei RNA sequencing

BACKGROUND: There are sex-specific differences in the prevalence, symptomology and course of psychiatric disorders. However, preclinical models have primarily used males, such that the molecular mechanisms underlying sex-specific differences in psychiatric disorders are not well established. METHODS...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Eamon, Arcego, Danusa Mar, Shen, Mo Jun, O'Toole, Nicholas, Wen, Xianglan, Nagy, Corina, Mostafavi, Sara, Craig, Kelly, Silveira, Patricia Pelufo, Rayan, Nirmala Arul, Diorio, Josie, Meaney, Michael J., Zhang, Tie-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432187/
https://www.ncbi.nlm.nih.gov/pubmed/37549631
http://dx.doi.org/10.1016/j.ebiom.2023.104749