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Low-oxygen tension augments chondrocyte sensitivity to biomimetic thermomechanical cues in cartilage-engineered constructs

Chondrocytes respond to various biophysical cues, including oxygen tension, transient thermal signals, and mechanical stimuli. However, understanding how these factors interact to establish a unique regulatory microenvironment for chondrocyte function remains unclear. Herein, we explore these intera...

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Detalles Bibliográficos
Autores principales: Stampoultzis, Theofanis, Guo, Yanheng, Nasrollahzadeh, Naser, Rana, Vijay Kumar, Karami, Peyman, Pioletti, Dominique P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432199/
https://www.ncbi.nlm.nih.gov/pubmed/37599834
http://dx.doi.org/10.1016/j.isci.2023.107491