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ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo

Chemotaxis drives diverse migrations important for development and involved in diseases, including cancer progression. Using border cells in the Drosophila egg chamber as a model for collective cell migration, we characterized the role of ArfGAP1 in regulating chemotaxis during this process. We foun...

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Detalles Bibliográficos
Autores principales: Boutet, Alison, Zeledon, Carlos, Emery, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432204/
https://www.ncbi.nlm.nih.gov/pubmed/37599820
http://dx.doi.org/10.1016/j.isci.2023.107467