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Fraxin inhibits melanogenesis by suppressing the ERK/MAPK pathway and antagonizes oxidative stress by activating the NRF2 pathway

Hyperpigmentation disorders, such as melasma and freckles, are highly prevalent and draw increasing attention. Patients thus tend to seek effective and safe cosmetic whitening agents. Fraxin, a bioactive substance extracted from Cortex Fraxini, possesses anti-inflammation and antioxidant properties....

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Detalles Bibliográficos
Autores principales: Luo, Liping, Yu, Xing, Zeng, Hongliang, Hu, Yibo, Jiang, Ling, Huang, Jinhua, Fu, Chuhan, Chen, Jing, Zeng, Qinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432208/
https://www.ncbi.nlm.nih.gov/pubmed/37600361
http://dx.doi.org/10.1016/j.heliyon.2023.e18929