Cargando…

Fraxin inhibits melanogenesis by suppressing the ERK/MAPK pathway and antagonizes oxidative stress by activating the NRF2 pathway

Hyperpigmentation disorders, such as melasma and freckles, are highly prevalent and draw increasing attention. Patients thus tend to seek effective and safe cosmetic whitening agents. Fraxin, a bioactive substance extracted from Cortex Fraxini, possesses anti-inflammation and antioxidant properties....

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Liping, Yu, Xing, Zeng, Hongliang, Hu, Yibo, Jiang, Ling, Huang, Jinhua, Fu, Chuhan, Chen, Jing, Zeng, Qinghai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432208/ https://www.ncbi.nlm.nih.gov/pubmed/37600361 http://dx.doi.org/10.1016/j.heliyon.2023.e18929

Ejemplares similares

Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca(2+)/Hh signaling pathway
por: Zhang, Lan, et al.
Publicado: (2023)

Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO‐1 pathway
por: Hu, Yibo, et al.
Publicado: (2020)

Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis
por: Chen, Rui, et al.
Publicado: (2022)

Roles of inflammation factors in melanogenesis
por: Fu, Chuhan, et al.
Publicado: (2020)

Is natural fraxin an overlooked radical scavenger?
por: Nam, Pham Cam, et al.
Publicado: (2021)

The investigation of the effect of fraxin on hepatotoxicity induced by cisplatin in rats
por: Ekinci̇-Akdemi̇r, Fazile Nur, et al.
Publicado: (2020)

Syntenin regulates melanogenesis via the p38 MAPK pathway
por: Sun, Lijun, et al.
Publicado: (2020)

Gomisin N Inhibits Melanogenesis through Regulating the PI3K/Akt and MAPK/ERK Signaling Pathways in Melanocytes
por: Chae, Jae Kyoung, et al.
Publicado: (2017)

The tRNA-derived fragment tRF-5022a positively regulates melanogenesis
por: Li, Si, et al.
Publicado: (2022)

MAPK-ERK Pathway
por: Park, Jong-In
Publicado: (2023)

The Extracts of Astragalus membranaceus Inhibit Melanogenesis through the ERK Signaling Pathway
por: Tsao, Yu-Tzu, et al.
Publicado: (2017)

MALAT1 participates in ultraviolet B-induced photo-aging via regulation of the ERK/MAPK signaling pathway
por: Lei, Li, et al.
Publicado: (2017)

LncRNA UCA1 promotes keratinocyte-driven inflammation via suppressing METTL14 and activating the HIF-1α/NF-κB axis in psoriasis
por: Hu, Yibo, et al.
Publicado: (2023)

ERK/MAPK signalling pathway and tumorigenesis
por: Guo, Yan-Jun, et al.
Publicado: (2020)

Fraxin Prevents Chemically Induced Hepatotoxicity by Reducing Oxidative Stress
por: Chang, Bo Yoon, et al.
Publicado: (2017)

Identification of the ceRNA networks in α-MSH-induced melanogenesis of melanocytes
por: Jiang, Ling, et al.
Publicado: (2020)

Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways
por: Wang, Wenbo, et al.
Publicado: (2016)

The Oxindole GW-5074 Inhibits JC Polyomavirus Infection and Spread by Antagonizing the MAPK-ERK Signaling Pathway
por: Kaiserman, Jacob, et al.
Publicado: (2023)

The Extract of Rhodobacter sphaeroides Inhibits Melanogenesis through the MEK/ERK Signaling Pathway
por: Liu, Wen-Sheng, et al.
Publicado: (2013)

Identification of Sitogluside as a Potential Skin-Pigmentation-Reducing Agent through Network Pharmacology
por: Guo, Haoran, et al.
Publicado: (2021)

Signaling Pathways in Melanogenesis
por: D’Mello, Stacey A. N., et al.
Publicado: (2016)

Anserine/Carnosine-Rich Extract from Thai Native Chicken Suppresses Melanogenesis via Activation of ERK Signaling Pathway
por: Teeravirote, Karuntarat, et al.
Publicado: (2022)

Effect of Sucrier Banana Peel Extracts on Inhibition of Melanogenesis through the ERK Signaling Pathway
por: Phacharapiyangkul, Naphichaya, et al.
Publicado: (2019)

Anthocyanins from Hibiscus syriacus L. Inhibit Melanogenesis by Activating the ERK Signaling Pathway
por: Karunarathne, Wisurumuni Arachchilage Hasitha Maduranga, et al.
Publicado: (2019)

Traditional Asian Herbs in Skin Whitening: The Current Development and Limitations
por: Hu, Yibo, et al.
Publicado: (2020)

Establishment and validation of evaluation models for post-inflammatory pigmentation abnormalities
por: Zhang, Yushan, et al.
Publicado: (2022)

Proteomic Response Revealed Signaling Pathways Involving in the Mechanism of Polymyxin B-Induced Melanogenesis
por: Zhang, Chuhan, et al.
Publicado: (2022)

The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes
por: Hseu, You-Cheng, et al.
Publicado: (2020)

Calycosin, a Common Dietary Isoflavonoid, Suppresses Melanogenesis through the Downregulation of PKA/CREB and p38 MAPK Signaling Pathways
por: Wu, Kun-Chang, et al.
Publicado: (2022)

MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma
por: Moon, Hyuk, et al.
Publicado: (2021)

Licorice zinc suppresses melanogenesis via inhibiting the activation of P38MAPK and JNK signaling pathway in C57BL/6J mice skin
por: Wang, Jing-yan, et al.
Publicado: (2022)

Crosstalk between G-quadruplex and ROS
por: Wu, Songjiang, et al.
Publicado: (2023)

Dynamic panoramic presentation of skin function after fractional CO(2) laser treatment
por: Guo, Haoran, et al.
Publicado: (2023)

α-Mangostin suppressed melanogenesis in B16F10 murine melanoma cells through GSK3β and ERK signaling pathway
por: Zhou, Siqi, et al.
Publicado: (2021)

Fraxin in Combination with Dexamethasone Attenuates LPS-Induced Liver and Heart Injury and Their Anticytokine Activity in Mice
por: Shaker, Nada Sahib, et al.
Publicado: (2023)

Activation of FXR Suppresses Esophageal Squamous Cell Carcinoma Through Antagonizing ERK1/2 Signaling Pathway
por: Feng, Qingqing, et al.
Publicado: (2021)

The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis
por: Kim, Jung-Min, et al.
Publicado: (2019)

Bakuchiol Suppresses Inflammatory Responses Via the Downregulation of the p38 MAPK/ERK Signaling Pathway
por: Lim, Hye-Sun, et al.
Publicado: (2019)

Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway
por: Zeng, Di, et al.
Publicado: (2021)

Amarogentin promotes osteoblast differentiation in oestrogen-deficiency-induced osteoporosis rats by modulating the Nrf-2/MAPK/ERK signalling pathway
por: Li, Sirui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2tv3u397s9rkul4s3u8rp5p2eq