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Longevity factor klotho enhances cognition in aged nonhuman primates

Cognitive dysfunction in aging is a major biomedical challenge. Whether treatment with klotho, a longevity factor, could enhance cognition in human-relevant models such as in nonhuman primates is unknown and represents a major knowledge gap in the path to therapeutics. We validated the rhesus form o...

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Detalles Bibliográficos
Autores principales: Castner, Stacy A., Gupta, Shweta, Wang, Dan, Moreno, Arturo J., Park, Cana, Chen, Chen, Poon, Yan, Groen, Aaron, Greenberg, Kenneth, David, Nathaniel, Boone, Tom, Baxter, Mark G., Williams, Graham V., Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432271/
https://www.ncbi.nlm.nih.gov/pubmed/37400721
http://dx.doi.org/10.1038/s43587-023-00441-x