Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

The concept of aging is complex, including many related phenotypes such as healthspan, lifespan, extreme longevity, frailty and epigenetic aging, suggesting shared biological underpinnings; however, aging-related endpoints have been primarily assessed individually. Using data from these traits and m...

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Detalles Bibliográficos
Autores principales: Rosoff, Daniel B., Mavromatis, Lucas A., Bell, Andrew S., Wagner, Josephin, Jung, Jeesun, Marioni, Riccardo E., Davey Smith, George, Horvath, Steve, Lohoff, Falk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432278/
https://www.ncbi.nlm.nih.gov/pubmed/37550455
http://dx.doi.org/10.1038/s43587-023-00455-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432278/
https://www.ncbi.nlm.nih.gov/pubmed/37550455
http://dx.doi.org/10.1038/s43587-023-00455-5

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