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An Imbalance in the Pro/mature BDNF Ratio Occurs in Multiple Brain Regions During Normal Ageing in Wild-Type Mice

The early transition to Alzheimer’s disease is characterized by a period of accelerated brain atrophy that exceeds normal ageing. Identifying the molecular basis of this atrophy could facilitate the discovery of novel drug targets. The precursor of brain-derived neurotrophic factor, a well character...

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Detalles Bibliográficos
Autores principales: Cade, Shaun, Zhou, Xin-Fu, Bobrovskaya, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432372/
https://www.ncbi.nlm.nih.gov/pubmed/37314606
http://dx.doi.org/10.1007/s12031-023-02131-0