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Modeling and optimization of parallelized immunomagnetic nanopore sorting for surface marker specific isolation of extracellular vesicles from complex media

The isolation of specific subpopulations of extracellular vesicles (EVs) based on their expression of surface markers poses a significant challenge due to their nanoscale size (< 800 nm), their heterogeneous surface marker expression, and the vast number of background EVs present in clinical spec...

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Detalles Bibliográficos
Autores principales: Lin, Andrew A., Shen, Hanfei, Spychalski, Griffin, Carpenter, Erica L., Issadore, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432479/
https://www.ncbi.nlm.nih.gov/pubmed/37587235
http://dx.doi.org/10.1038/s41598-023-39746-7