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Evaluation of drug-induced liver toxicity of trovafloxacin and levofloxacin in a human microphysiological liver model
Drug-induced liver injury induced by already approved substances is a major threat to human patients, potentially resulting in drug withdrawal and substantial loss of financial resources in the pharmaceutical industry. Trovafloxacin, a broad-spectrum fluoroquinolone, was found to have unexpected sid...
Autores principales: | Kaden, Tim, Graf, Katja, Rennert, Knut, Li, Ruoya, Mosig, Alexander S., Raasch, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432496/ https://www.ncbi.nlm.nih.gov/pubmed/37587168 http://dx.doi.org/10.1038/s41598-023-40004-z |
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