IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice

Cardiac fibrosis is a common feature of chronic heart failure. Iroquois homeobox (IRX) family of transcription factors plays important roles in heart development; however, the role of IRX2 in cardiac fibrosis has not been clarified. Here we report that IRX2 expression is significantly upregulated in...

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Detalles Bibliográficos
Autores principales: Ma, Zhen-Guo, Yuan, Yu-Pei, Fan, Di, Zhang, Xin, Teng, Teng, Song, Peng, Kong, Chun-Yan, Hu, Can, Wei, Wen-Ying, Tang, Qi-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432509/
https://www.ncbi.nlm.nih.gov/pubmed/37587150
http://dx.doi.org/10.1038/s41467-023-40639-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432509/
https://www.ncbi.nlm.nih.gov/pubmed/37587150
http://dx.doi.org/10.1038/s41467-023-40639-6

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