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IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice
Cardiac fibrosis is a common feature of chronic heart failure. Iroquois homeobox (IRX) family of transcription factors plays important roles in heart development; however, the role of IRX2 in cardiac fibrosis has not been clarified. Here we report that IRX2 expression is significantly upregulated in...
Autores principales: | Ma, Zhen-Guo, Yuan, Yu-Pei, Fan, Di, Zhang, Xin, Teng, Teng, Song, Peng, Kong, Chun-Yan, Hu, Can, Wei, Wen-Ying, Tang, Qi-Zhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432509/ https://www.ncbi.nlm.nih.gov/pubmed/37587150 http://dx.doi.org/10.1038/s41467-023-40639-6 |
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