Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

The beneficial effects of physical activity on brain ageing are well recognised, with exerkines, factors that are secreted into the circulation in response to exercise, emerging as likely mediators of this response. However, the source and identity of these exerkines remain unclear. Here we provide...

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Detalles Bibliográficos
Autores principales: Leiter, Odette, Brici, David, Fletcher, Stephen J., Yong, Xuan Ling Hilary, Widagdo, Jocelyn, Matigian, Nicholas, Schroer, Adam B., Bieri, Gregor, Blackmore, Daniel G., Bartlett, Perry F., Anggono, Victor, Villeda, Saul A., Walker, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432533/
https://www.ncbi.nlm.nih.gov/pubmed/37587147
http://dx.doi.org/10.1038/s41467-023-39873-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432533/
https://www.ncbi.nlm.nih.gov/pubmed/37587147
http://dx.doi.org/10.1038/s41467-023-39873-9

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