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Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts

Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) play critical roles in human health. Prior genome-wide association studies (GWAS) of n-3 and n-6 PUFAs in European Americans from the CHARGE Consortium have documented strong genetic signals in/near the FADS locus on chromosome 11....

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Detalles Bibliográficos
Autores principales: Yang, Chaojie, Veenstra, Jenna, Bartz, Traci M., Pahl, Matthew C., Hallmark, Brian, Chen, Yii-Der Ida, Westra, Jason, Steffen, Lyn M., Brown, Christopher D., Siscovick, David, Tsai, Michael Y., Wood, Alexis C., Rich, Stephen S., Smith, Caren E., O’Connor, Timothy D., Mozaffarian, Dariush, Grant, Struan F. A., Chilton, Floyd H., Tintle, Nathan L., Lemaitre, Rozenn N., Manichaikul, Ani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432561/
https://www.ncbi.nlm.nih.gov/pubmed/37587153
http://dx.doi.org/10.1038/s42003-023-05219-w