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Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells

Leukemic-stem-cell-specific targeting may improve the survival of patients with acute myeloid leukemia (AML) by avoiding the ablative effects of standard regimens on normal hematopoiesis. Herein, we perform an unbiased screening of compounds targeting cell surface proteins and identify clinically us...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Nistala, Ravi, Cao, Min, Pan, Yi, Behrens, Madelaine, Doll, Donald, Hammer, Richard D., Nistala, Puja, Chang, Hui-Ming, Yeh, Edward T.H., Kang, XunLei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432577/
https://www.ncbi.nlm.nih.gov/pubmed/36807138
http://dx.doi.org/10.1016/j.celrep.2023.112105