PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression

BACKGROUND: Ovarian adenocarcinoma (OVAD) frequently metastasizes to the peritoneal cavity and manifests by the formation of ascites, which constitutes a tumor-promoting microenvironment. In the peritoneal cavity, two developmentally, phenotypically and functionally distinct macrophage subsets, immu...

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Detalles Bibliográficos
Autores principales: Prat, Mélissa, Coulson, Kimberley, Blot, Clément, Jacquemin, Godefroy, Romano, Mathilde, Renoud, Marie-Laure, AlaEddine, Mohamad, Le Naour, Augustin, Authier, Hélène, Rahabi, Mouna Chirine, Benmoussa, Khaddouj, Salon, Marie, Parny, Mélissa, Delord, Jean-Pierre, Ferron, Gwenaël, Lefèvre, Lise, Couderc, Bettina, Coste, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432661/
https://www.ncbi.nlm.nih.gov/pubmed/37586764
http://dx.doi.org/10.1136/jitc-2023-007031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432661/
https://www.ncbi.nlm.nih.gov/pubmed/37586764
http://dx.doi.org/10.1136/jitc-2023-007031

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